Mhedzisiro: Kuvandudzwa kweplatelet-rich fibrin (PRF) kwakarerutsa nzira yekugadzirira yeplatelet-concentrated biomaterials, senge platelet-rich plasma (PRP), uye yakafambisa kiriniki yavo yekushandisa.PRF's kliniki inoshanda yakagara ichiratidzwa mune pre-kiriniki uye kliniki zvidzidzo;zvisinei, zvichiri kukakavara kana zvinhu zvekukura zvakanyanya kuiswa muPRF gadziriro yekufambisa maronda ekupora uye kuvandudzwa kwetishu.Kuti tigadzirise nyaya iyi, takaita ongororo yekuenzanisa yekukura kwezvinhu zvirimo muPRP uye zvinobva pairi, senge advanced PRF (A-PRF) uye yakanyanya kukura zvinhu (CGF).
Nzira: PRP uye zvinobva mairi zvakagadzirirwa kubva kune imwechete peripheral masampu eropa akaunganidzwa kubva kune vane hutano vanopa.A-PRF uye CGF gadziriro dzakaitwa homogenized uye centrifuged kugadzira zvinyorwa.Platelet uye chena masero eropa muA-PRF uye CGF gadziriro dzakatemerwa nekubvisa iwo maverengero mumasero matsvuku eropa zvikamu, supernatant acellular serum zvikamu, uye A-PRF/CGF exudate zvikamu kubva kune izvo kuverenga kwesero ropa samples.Mafungiro ekukura kwezvinhu (TGF-β1, PDGF-BB, VEGF) uye pro-inflammatory cytokines (IL-1β, IL-6) yakagadziriswa kushandisa ELISA kits.
Mhedzisiro: Kuenzaniswa nePRP gadziriro, ese A-PRF uye CGF zvinyorwa zvine zvinoenderana kana mazinga epamusoro emaplatelet uye platelet-yakatorwa kukura zvinhu.Muchiyero chekuwedzera kwesero, zvese A-PRF uye CGF zvinyorwa zvakakurudzira zvakanyanya kuwanda kwemasero emunhu periosteal pasina kuderedzwa kwakakosha pamadosi epamusoro.
Mhedziso: Aya data anoratidza zvakajeka kuti ese A-PRF uye CGF gadziriro dzine huwandu hwakakura hwekukura zvinhu zvinokwanisa kukurudzira periosteal cell kuwanda, zvichiratidza kuti A-PRF neCGF gadziriro dzinoshanda kwete sechikafu zvinhu chete asiwo sedziva rekuunza zvimwe. kukura zvinhu panzvimbo yekushandisa.
Keywords: Growth factor, Platelet-rich plasma, Platelet-rich fibrin, Plasma yakawanda mukukura kwezvinhu, Yakanyanya kukura zvinhu Zvipfupiso: ACD, Acid citrate dextrose solution;ANOVA, Kuongororwa kwekusiyana;A-PRF, Advanced platelet-rich fibrin;A-PRfext, A-PRF yakatorwa;CGF, Yakanyanya kukura zvinhu;CGFext, CGF yakabudiswa;ELISA, Enzyme-yakabatana immunosorbent assay;IL-1β, Interleukin-1β;IL-6, Interleukin-6;PDGF-BB, Platelet-derived growth factor-BB;PLT, Platelet;PRGF, Plasma yakapfuma mukukura zvinhu;PRP, Platelet-rich plasma;RBC, Tsvuku.
Nguva yekutumira: Oct-12-2022